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What happens to the fat we take in meals? When we eat fat, it is digested and absorbed in our gastrointestinal tract. Some fat is not absorbed and excreted. Fat is one of the three macronutrients of human food, along with carbohydrates and proteins. Fat is a very good source of energy and essential for cell formation and vitamin absorption. It is vital for good health. However, an excess of fat is hazardous for our health. Let us delve into the fate of fat in our body. Digestion of fat:  Lipids are large molecules, and unlike carbohydrates and proteins, they are not soluble in water and do not mix with the watery blood. So, they like to cluster together in large droplets in a liquid surrounding the gastrointestinal tract. The digestive process breaks those large droplets of fat into smaller droplets, and then enzymes digest lipid molecules using enzymes called lipase. In the mouth:  Chewing breaks food into smaller particles and mixes them with saliva. Lingual lipase be

Gastrointestinal Tract | Physiology

Introduction of Gastrointestinal Tract

This article discusses different parts of the gastrointestinal tract. Learn about the structure, blood supply, and nervous supply here.

Keywords: Meissner's plexus, Gastrointestinal bleeding, Gastrointestinal agents, Gastrointestinal symptoms, Myenteric plexus, Muscularis mucosa.

Table of contents

1.

Parts

2.

Functions 

3.

Structure

4.

Nervous control

5.

Parasympathetic & sympathetic system

6.

Blood supply


About' totalphysiology.com.'

This article is part of my mission to provide trustworthy recent health information to support the general public, patients, and professionals globally.

Here, you will find human Physiology, Anatomy, and health-related topics.

This article is intended for an international audience of medical care providers and learners.

This activity aims for learners to better apply the latest scientific knowledge.

Upon completing the article, you will have increased knowledge regarding the subject and use it with great confidence.

Different parts of the gastrointestinal tract from above downwards are:

1. Mouth

2. Tongue

3. Pharynx

4. Oesophagus

5. Stomach

6. Small intestine

7. Large intestine

8. Rectum

9. Anus

The total length is 30 ft /9 meters at autopsy but shorter in the living due to contraction.




Accessory organs of the gastrointestinal tract are

  1. Tongue

        2. Salivary Glands

        3. Liver

   4. Pancreas

         5. Gall Bladder

The gastrointestinal  tract: 

A. Provides the body with a continual supply of:

1. Nutrients

2. Water

3. Electrolytes

4. Vitamins

B. And finally, expel the unabsorbable excreta outside the body.

To perform its functions, the gastrointestinal tract  causes  :

1. Mastication of food

2. Movement of food through the alimentary tract.

3. Secretion of digestive juices from the gastrointestinal tract and accessory organs of the gastrointestinal tract.

4. Digestion of the food and.

5. Absorption of the product of digestion, water, electrolytes, and vitamins.

6. Blood circulation through the alimentary tract to carry away the absorbed substances  to the liver and

The gastrointestinal tract functions are controlled by the local nervous system, central nervous system, and hormones secreted in the body.        

The general structure of the gastrointestinal tract :

The alimentary tract has a more or less uniform structure in a cross-section with some regional variations.

The following layers are present in a typical cross-section of the alimentary tract  from the outer surface  inwards:

The serosal layer.

A smooth muscle layer of longitudinal and circular muscles    

The submucosa and The mucous membrane



                                                Structure of  gastrointestinal tract


The mucous membrane has 3 layers from inside to outside:

The epithelial layer: a single layer of columnar cells arising from the basement membrane. It lines the lumen of the alimentary tract.

Lamina propria, or basement membrane, is a layer  of reticular tissue  and  is next to the epithelial layer and

Muscularis mucosa :  a thin layer of muscules that separates lamina propria  from the submucosa. The muscularis mucosa is outside the lamina propria and separates it from the submucosa. It is present from the esophagus to the upper rectum. The muscularis mucosa is also known as lamina muscularis mucosa. Lamina stands for a thin layer. Muscularis mucosa comprises several thin layers of smooth muscle fibers arranged in different ways, keeping the mucosal surface and underlying glands in a constant state of gentle movements to expel glandular contents and enhance contact between epithelium and the contents of the lumen. It folds in the lumen, so the surface area increases for digestion and absorption. It goes into the villi, which protrudes into the gastric lumen. When it contracts, it pushes the absorbed fat into the lacteals and, when it contracts alternately, causes side-to-side movements to absorb the nutrients. It has no role in major movements of the small intestine.

The submucosa is present between the mucous membrane and the muscular layer. It contains areolar tissue with blood vessels, nerves, and lymphatics.

The muscular layer has two parts: the outer longitudinal and the inner circular.

The longitudinal layer of smooth muscle is present throughout the alimentary tract. In the large intestine, this layer exhibits bands  -thickening at fixed positions of the large intestine. These bands are known as Taenia coli.

The inner circular layer of smooth muscle is regularly present around the alimentary tract with some regional variations: The smooth muscles of the circular layer become thick around orifices to form sphincters.

An oblique layer of smooth muscles in the stomach is present deep in the circular layer.

The serosal layer is the outermost layer of the alimentary tract. The visceral peritoneum forms it. It is worth mentioning that the visceral peritoneum forms the outer layer of the whole gastrointestinal except the esophagus and the distal rectum.

Neural control of the alimentary tract :

The alimentary tract has a nervous system called the enteric nervous system. It lies entirely in the gut wall from the esophagus to the anus. The number of neurons in this enteric nervous system is about 100 million. The Enteric nervous system is essential in controlling alimentary tract movements and secretion.

Types of Enteric Nervous System This is composed mainly of two interconnected plexuses:

1. The myenteric plexus is the outer plexus between the longitudinal and circular muscle layers and mainly controls gastrointestinal movements.

2. The Meissner's or submucosal plexus is the inner plexus present in the submucosal layer. It is mainly concerned with secretion and local blood flow.

The plexuses are connected. They are also associated with the extrinsic sympathetic and parasympathetic fibers.

The Enteric nervous system can function independently, but extrinsic sympathetic and parasympathetic nervous systems may influence it.

Functions of sympathetic and parasympathetic nervous systems :

Sympathetic nervous system: its stimulation decreases motility by causing relaxation of intestinal smooth muscles and contracting the sphincters.

Parasympathetic nervous system:  Its stimulation increases motility by contracting intestinal smooth muscles and relaxing the sphincters. It also increases gland secretion.

Reflexes in the alimentary tract:

Two types of reflexes are present in the gastrointestinal tract

Long reflexes: efferents from GIT enter the spinal cord or brain –the center of reflex- afferents emerge from the central nervous system and finally reach the GIT effector organ.

 In short, the reflexes afferent nerve, the center, and the efferent nerve area in the wall of the GIT.CNS is not involved.

GIT  blood flow is from the splanchnic circulation –blood flows through the gut, liver, spleen, and pancreas to the liver.

In the portal circulation, two capillary beds are in series, so blood collected from one capillary bed drains into another.

The first capillary bed is in the gut.

The second capillary bed is in the liver.

In splanchnic circulation, blood flows from the spleen, pancreas, and liver to the gut. From the gut, the blood flows into the liver by the hepatic portal vein. Finally, the hepatic portal vein drains into the vena cava.

Hashtags: Meissner's plexus#Gastrointestinal bleeding# Gastrointestinal agents# Gastrointestinal symptoms# Myenteric plexus# Muscularis mucosa.

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Internal links:

https://blog.totalphysiology.com/2021/06/movements-of-stomach-we-must-know.html

https://blog.totalphysiology.com/2021/05/deglutition-edited-we-must-know.html

https://blog.totalphysiology.com/2021/05/gut-brain-axis-you-must-know.html

https://blog.totalphysiology.com/2021/03/small-intestine-we-must-know.html

External links:https://learn-and-fly.co.in/2022/05/18/development-of-the-gastrointestinal-tract/

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