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Polycythemia| Polycythemia Vera

Polycythemia Rubra Vera  |Polycythemia  Introduction: This article discusses different causes of polycythemia and methods employed to diagnose  polycythemia.   Here, learn about the tests, procedures, indications, and more. Keywords :   Polycythemia | P olycythemia vera |Relative  polycythemia |Primary  polycythemia| CBC test |Asolute|Blood disorder|Myeloprolerative disease| Pluripotent    Table of contents 1. Introduction 2. Classification  3. Causes 4. Signs and Symptoms 5. Diagnosis and Treatment About’ totalphysiology.com.’ This article is part of my mission to provide trustworthy recent health information to support the general public, patients, and professionals globally. Here, you will find human Physiology and health-related topics. This article is intended for all learners and medical care providers. This activity aims for learners to bet

Fever Producing Substances: Pyrogens

Fever Producing Substances Fever causing Pyrogen is usually derived from microorganisms.   Keywords: Pyrogens, Cytokines, Interleukin, Endogenous, PGF2, Exogenous, Lipopolysaccharides (LPS), LPB- LPS, Tumor necrosis factor – α, Arachidonic -acid, PGE2. What is pyrogen? The fever-producing substance is pyrogen. The pyrogen is usually derived from microorganisms such as bacteria, viruses, viroids, etc. When present in large amount may lead to severe inflammation when not treated, it may lead to shock, multi-organ failure, and even death.    Exogenous Pyrogens    Microbial:   Virus, Bacteria, Yeast, Fungus, Malarial parasites                      Lipopolysaccharide in gram-negative bacteria wall.                     Lipoteichoic in gram-positive bacteria.    Non–microbial:                                                           Nonself: Some drugs, e.g.,   Colchicin                   Environment pollution    Self: Antigen-antibody complexes              Metabolic produ